An efficient simultaneous electrochemical detection of nanomolar epinephrine and uric acid using low temperature synthesized nano-sized copper telluride

• Main Authors: Pradhan, Susmita, Bhattacharyya Banerjee, Mahuya, Biswas, Sudip, Hamizi, Nor Aliya, Das, Dipak K., Bhar, Radhaballabh, Bandyopadhyay, Rajib, Pramanik, Panchanan
• Format: Article
• Published: Wiley-V C H Verlag 2021
• Subjects: QD Chemistry
• Online Access: http://eprints.um.edu.my/33973/

Herein we developed a simple, cost effective, electrochemical sensor based on nanosized copper telluride (nps-CuTe) for simultaneous detection of epinephrine (EP) and uric acid (UA). Voltammetric responses suggests dramatical improvement of electrocatalytic properties of both molecules by incorporating CuTe nps into unmodified graphite paste electrode (bare GP). Differential pulse voltammetric (DPV) measurement depicts large potential separation of 128 mV between EP and UA, allows their simultaneous determination from binary mixture. Under optimized condition, CuTe modified graphite paste electrode (CuTe/GP) manifested linear relationships of EP and UA in the range of 5-60 mu M and 5-120 mu M with detection limit (S/N=3) of 18 nM and 32 nM respectively. Moreover, CuTe/GP showed satisfactory response towards pharmaceutical and clinical samples for determining EP and UA concentrations.