Alpha-Amylase and dipeptidyl peptidase-4 (DPP-4) inhibitory effects of Melicope latifolia bark extracts and identification of bioactive constituents using in vitro and in silico approaches

• Main Authors: Quek, Alexandra, Kassim, Nur Kartinee, Lim, Pei Cee, Tan, Dai Chuan, Mohammad Latif, Muhammad Alif, Ismail, Amin, Shaari, Khozirah, Awang, Khalijah
• Format: Article
• Published: Taylor & Francis 2021
• Subjects: QD Chemistry
• Online Access: http://eprints.um.edu.my/33965/

Context Melicope latifolia (DC.) T. G. Hartley (Rutaceae) was reported to contain various phytochemicals including coumarins, flavonoids, and acetophenones. Objective This study investigates the antidiabetic and antioxidant effects of M. latifolia bark extracts, fractions, and isolated constituents....