Long-term Safety and Efficacy of Esketamine Nasal Spray Plus an Oral Antidepressant in Patients with Treatment-resistant Depression- an Asian Sub-group Analysis from the SUSTAIN-2 Study

• Main Authors: Jeon, Hong Jin, Ju, Po-Chung, Sulaiman, Ahmad Hatim, Aziz, Salina Abdul, Paik, Jong-Woo, Tan, Wilson, Bai, Daisy, Li, Cheng-Ta
• Format: Article
• Published: Korean Coll Neuropsychopharmacology 2022
• Subjects: R Medicine (General)
• Online Access: http://eprints.um.edu.my/33415/

Objective: To evaluate the long-term safety and efficacy of intranasal esketamine in patients with treatment-resistant depression from the Asian subgroup of the SUSTAIN-2 study. Methods: SUSTAIN-2 was a phase 3, open-label, single-arm, multicenter study comprising a 4-week screening, 4-week inductio...