Design, synthesis, characterization and cytotoxic activity of new ortho-hydroxy and indole-chalcone derivatives against breast cancer cells (MCF-7)

Twenty-seven new ortho-hydroxy chalcone and a series of indole-chalcone derivatives have been designed and synthesized. The structures of all newly-synthesized compounds were characterized by different spectroscopic techniques and the interactions with tubulin were evaluated for antiproliferative ac...

Full description

Saved in:
Bibliographic Details
Main Authors: Jumaah, Maadh, Khairuddean, Melati, Owaid, Sohaib Jumaah, Zakaria, Nurhisyam, Mohd Arshad, Norhafiza, Nagoor, Noor Hasima, Taib, Mohamad Nurul Azmi Mohamad
Format: Article
Published: Springer Verlag 2022
Subjects:
Online Access:http://eprints.um.edu.my/33356/
Tags: Add Tag
No Tags, Be the first to tag this record!