Accelerated nucleophilic substitution reactions of dansyl chloride with aniline under ambient conditions via dual-tip reactive paper spray

• Main Authors: Sarih, Norfatirah Muhamad, Romero-Perez, David, Bastani, Behnam, Rauytanapanit, Monrawat, Boisdon, Cedric, Praneenararat, Thanit, Tajuddin, Hairul Anuar, Abdullah, Zanariah, Badu-Tawiah, Abraham K., Maher, Simon
• Format: Article
• Published: Nature Portfolio 2020
• Subjects: Q Science (General); T Technology (General)
• Online Access: http://eprints.um.edu.my/31733/

Paper spray ionization (PSI) mass spectrometry (MS) is an emerging tool for ambient reaction monitoring via microdroplet reaction acceleration. PSI-MS was used to accelerate and monitor the time course of the reaction of dansyl chloride with aniline, in acetonitrile, to produce dansyl aniline. Three...