Mechanisms underlining gender differences in Phenylephrine contraction of normoglycaemic and short-term Streptozotocin-induced diabetic WKY rat aorta

• Main Authors: Aloysuis, U.I., Achike, F.I., Mustafa, Mohd Rais
• Format: Article
• Language: English
• Published: Elsevier 2011
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/3031/1/Mechanisms_underlining_gender_differences_in_Phenylephrine_contraction_of_normoglycaemic.pdf; http://eprints.um.edu.my/3031/; http://www.sciencedirect.com/science/article/pii/S1537189111003776

The female gender reduces the risk, but succumbs more to cardiovascular disease. The hypothesis that shortterm 8 weeks) Streptozotocin-induced diabetes could produce greater female thanmale vascular tissue reactivity and themechanistic basiswere explored. Aortic ring responses to Phenylephrine were...