Zerumbone mediates apoptosis and induces secretion of proinflammatory cytokines in breast carcinoma cell culture

• Main Authors: Barathan, Muttiah, Vellasamy, Kumutha Malar, Ibrahim, Zaridatul Aini, Mariappan, Vanitha, Hoong, See Mee, Vadivelu, Jamuna
• Format: Article
• Published: Mashhad Univ Med Sciences 2021
• Subjects: RM Therapeutics. Pharmacology; RS Pharmacy and materia medica
• Online Access: http://eprints.um.edu.my/28471/

Objective(s): To investigate the potential anti-breast cancer activity of zerumbone in regulating apoptotic mediators and cytokines in comparison with paclitaxel (positive control). Materials and Methods: In this study, assays such as viability, apoptosis, reactive oxygen species, cell cycle, DNA fr...