A review of commercial developments and recent laboratory research of dialyzers and membranes for hemodialysis application

Dialyzers have been commercially used for hemodialysis application since the 1950s, but progress in improving their efficiencies has never stopped over the decades. This article aims to provide an up-to-date review on the commercial developments and recent laboratory research of dialyzers for hemodi...

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Main Authors: Said, Noresah, Lau, Woei Jye, Ho, Yeek-Chia, Lim, Soo Kun, Abidin, Muhammad Nidzhom Zainol, Ismail, Ahmad Fauzi
Format: Article
Published: MDPI 2021
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Online Access:http://eprints.um.edu.my/28179/
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spelling my.um.eprints.281792022-07-26T04:11:41Z http://eprints.um.edu.my/28179/ A review of commercial developments and recent laboratory research of dialyzers and membranes for hemodialysis application Said, Noresah Lau, Woei Jye Ho, Yeek-Chia Lim, Soo Kun Abidin, Muhammad Nidzhom Zainol Ismail, Ahmad Fauzi R Medicine (General) Dialyzers have been commercially used for hemodialysis application since the 1950s, but progress in improving their efficiencies has never stopped over the decades. This article aims to provide an up-to-date review on the commercial developments and recent laboratory research of dialyzers for hemodialysis application and to discuss the technical aspects of dialyzer development, including hollow fiber membrane materials, dialyzer design, sterilization processes and flow simulation. The technical challenges of dialyzers are also highlighted in this review, which discusses the research areas that need to be prioritized to further improve the properties of dialyzers, such as flux, biocompatibility, flow distribution and urea clearance rate. We hope this review article can provide insights to researchers in developing/designing an ideal dialyzer that can bring the best hemodialysis treatment outcomes to kidney disease patients.</p> MDPI 2021-10 Article PeerReviewed Said, Noresah and Lau, Woei Jye and Ho, Yeek-Chia and Lim, Soo Kun and Abidin, Muhammad Nidzhom Zainol and Ismail, Ahmad Fauzi (2021) A review of commercial developments and recent laboratory research of dialyzers and membranes for hemodialysis application. Membranes, 11 (10). ISSN 2077-0375, DOI https://doi.org/10.3390/membranes11100767 <https://doi.org/10.3390/membranes11100767>. 10.3390/membranes11100767
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine (General)
spellingShingle R Medicine (General)
Said, Noresah
Lau, Woei Jye
Ho, Yeek-Chia
Lim, Soo Kun
Abidin, Muhammad Nidzhom Zainol
Ismail, Ahmad Fauzi
A review of commercial developments and recent laboratory research of dialyzers and membranes for hemodialysis application
description Dialyzers have been commercially used for hemodialysis application since the 1950s, but progress in improving their efficiencies has never stopped over the decades. This article aims to provide an up-to-date review on the commercial developments and recent laboratory research of dialyzers for hemodialysis application and to discuss the technical aspects of dialyzer development, including hollow fiber membrane materials, dialyzer design, sterilization processes and flow simulation. The technical challenges of dialyzers are also highlighted in this review, which discusses the research areas that need to be prioritized to further improve the properties of dialyzers, such as flux, biocompatibility, flow distribution and urea clearance rate. We hope this review article can provide insights to researchers in developing/designing an ideal dialyzer that can bring the best hemodialysis treatment outcomes to kidney disease patients.</p>
format Article
author Said, Noresah
Lau, Woei Jye
Ho, Yeek-Chia
Lim, Soo Kun
Abidin, Muhammad Nidzhom Zainol
Ismail, Ahmad Fauzi
author_facet Said, Noresah
Lau, Woei Jye
Ho, Yeek-Chia
Lim, Soo Kun
Abidin, Muhammad Nidzhom Zainol
Ismail, Ahmad Fauzi
author_sort Said, Noresah
title A review of commercial developments and recent laboratory research of dialyzers and membranes for hemodialysis application
title_short A review of commercial developments and recent laboratory research of dialyzers and membranes for hemodialysis application
title_full A review of commercial developments and recent laboratory research of dialyzers and membranes for hemodialysis application
title_fullStr A review of commercial developments and recent laboratory research of dialyzers and membranes for hemodialysis application
title_full_unstemmed A review of commercial developments and recent laboratory research of dialyzers and membranes for hemodialysis application
title_sort review of commercial developments and recent laboratory research of dialyzers and membranes for hemodialysis application
publisher MDPI
publishDate 2021
url http://eprints.um.edu.my/28179/
_version_ 1739828445221748736
score 13.19449