Synthesized 2-trifluoromethylquinazolines and quinazolinones protect bv2 and n2a cells against lps- and h2o2-induced cytotoxicity

• Main Authors: Nallathamby, Neeranjini, Phan, Chia-Wei, Sova, Matej, Saso, Luciano, Sabaratnam, Vikineswary
• Format: Article
• Published: BENTHAM SCIENCE PUBL LTD 2021
• Subjects: Q Science (General); RS Pharmacy and materia medica
• Online Access: http://eprints.um.edu.my/28156/

Background: Microglia are associated with neuroinflammation, which play a key role in the pathogenesis of neurodegenerative diseases. It has been reported that some quinazolines and quinazolinones possess anti-inflammatory properties. However, the pharmacological properties of certain quinazoline de...