Hydroxychavicol, a polyphenol from Piper betle leaf extract, induces cell cycle arrest and apoptosis in TP53-resistant HT-29 colon cancer cells

• المؤلفون الرئيسيون: Rajedadram, Aiysvariyah, Pin, Kar Yong, Ling, Sui Kiong, Yan, See Wan, Looi, Mee Lee
• التنسيق: مقال
• منشور في: Springer Verlag 2021
• الموضوعات: QD Chemistry; QR Microbiology
• الوصول للمادة أونلاين: http://eprints.um.edu.my/27945/

This study aims to elucidate the antiproliferative mechanism of hydroxychavicol (HC). Its effects on cell cycle, apoptosis, and the expression of c-Jun N-terminal kinase (JNK) and P38 mitogen-activated protein kinase (MAPK) in HT-29 colon cancer cells were investigated. HC was isolated from Piper be...