Itraconazole-induced Torsade de Pointes in a patient receiving methadone substitution therapy

• Main Authors: Robson, N.Z., Vicknasingam, B., Narayanan, S.
• Format: Article
• Language: English
• Published: Wiley-blackwell publishing, inc Malden 2009
• Subjects: H Social Sciences (General); R Medicine
• Online Access: http://eprints.um.edu.my/2687/1/Drug_and_Alcohol_review-Itraconazole_induced_Torsade_de_Pointes-11th_August_2009.pdf; http://eprints.um.edu.my/2687/; http://www.scopus.com/record/display.url?eid=2-s2.0-76949089330&origin=inward&txGid=EhVvZxieT5uUjQ86CuAhfvM%3a2

Issues. Methadone, a pharmacological agent used to treat heroin dependence is relatively safe, but may cause cardiac arrhythmias in the concurrent presence of other risk factors. Approach and Key Findings. This case report highlights the risk of Torsade de Pointes, a life-threatening cardiac arrhyth...