Cover Image

Human immunodeficiency virus type 1 subtypes among Malaysian intravenous drug users

The HIV-1 genetic variation in 60 infected Malaysian intravenous drug users (IDU) was studied by comparison of the nucleotide sequences and their predicted amino acid sequences in the V3 loop of the external glycoprotein gp120. In this study, HIV-1 B, C and E subtypes were identified among Malaysian...

Full description

Saved in:
Bibliographic Details
Main Authors: Saraswathy, T.S., Ng, Kee Peng, Sinniah, M.
Format: Article
Published: SEAMEO Regional Tropical Medicine and Public Health Network 2000
Subjects:
R Medicine
Online Access:http://eprints.um.edu.my/26055/
https://www.tm.mahidol.ac.th/seameo/2000_31_2/14-2418.pdf
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.um.eprints.26055
record_format eprints
spelling my.um.eprints.260552021-10-20T06:41:02Z http://eprints.um.edu.my/26055/ Human immunodeficiency virus type 1 subtypes among Malaysian intravenous drug users Saraswathy, T.S. Ng, Kee Peng Sinniah, M. R Medicine The HIV-1 genetic variation in 60 infected Malaysian intravenous drug users (IDU) was studied by comparison of the nucleotide sequences and their predicted amino acid sequences in the V3 loop of the external glycoprotein gp120. In this study, HIV-1 B, C and E subtypes were identified among Malaysian IDU, with HIV-1 B being the predominant subtype (91.7%). HIV-1 C and HIV-1 E were minority subtypes among Malaysian IDU. Analysis of the amino acid alignment of the C2-V3 region of the env gene suggests a genetic relationship between Thai and Malaysian B and E subtype strains. This study serves as a baseline for monitoring HIV-1 genetic diversity and spread in Malaysia. SEAMEO Regional Tropical Medicine and Public Health Network 2000 Article PeerReviewed Saraswathy, T.S. and Ng, Kee Peng and Sinniah, M. (2000) Human immunodeficiency virus type 1 subtypes among Malaysian intravenous drug users. Southeast Asian Journal of Tropical Medicine and Public Health, 31 (2). pp. 283-286. ISSN 0125-1562 https://www.tm.mahidol.ac.th/seameo/2000_31_2/14-2418.pdf
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine
spellingShingle R Medicine
Saraswathy, T.S.
Ng, Kee Peng
Sinniah, M.
Human immunodeficiency virus type 1 subtypes among Malaysian intravenous drug users
description The HIV-1 genetic variation in 60 infected Malaysian intravenous drug users (IDU) was studied by comparison of the nucleotide sequences and their predicted amino acid sequences in the V3 loop of the external glycoprotein gp120. In this study, HIV-1 B, C and E subtypes were identified among Malaysian IDU, with HIV-1 B being the predominant subtype (91.7%). HIV-1 C and HIV-1 E were minority subtypes among Malaysian IDU. Analysis of the amino acid alignment of the C2-V3 region of the env gene suggests a genetic relationship between Thai and Malaysian B and E subtype strains. This study serves as a baseline for monitoring HIV-1 genetic diversity and spread in Malaysia.
format Article
author Saraswathy, T.S.
Ng, Kee Peng
Sinniah, M.
author_facet Saraswathy, T.S.
Ng, Kee Peng
Sinniah, M.
author_sort Saraswathy, T.S.
title Human immunodeficiency virus type 1 subtypes among Malaysian intravenous drug users
title_short Human immunodeficiency virus type 1 subtypes among Malaysian intravenous drug users
title_full Human immunodeficiency virus type 1 subtypes among Malaysian intravenous drug users
title_fullStr Human immunodeficiency virus type 1 subtypes among Malaysian intravenous drug users
title_full_unstemmed Human immunodeficiency virus type 1 subtypes among Malaysian intravenous drug users
title_sort human immunodeficiency virus type 1 subtypes among malaysian intravenous drug users
publisher SEAMEO Regional Tropical Medicine and Public Health Network
publishDate 2000
url http://eprints.um.edu.my/26055/
https://www.tm.mahidol.ac.th/seameo/2000_31_2/14-2418.pdf
_version_ 1715190263664607232
score 13.164666

Similar Items