Integrating multiple genomic technologies to investigate an outbreak of carbapenemase-producing Enterobacter hormaechei

• Main Authors: Roberts, Leah W., Harris, Patrick N.A., Forde, Brian M., Ben Zakour, Nouri L., Catchpoole, Elizabeth, Stanton-Cook, Mitchell, Phan, Minh-Duy, Sidjabat, Hanna E., Bergh, Haakon, Heney, Claire, Gawthorne, Jayde A., Lipman, Jeffrey, Allworth, Anthony, Chan, Kok Gan, Chong, Teik Min, Yin, Wai Fong, Schembri, Mark A., Paterson, David L., Beatson, Scott A.
• Format: Article
• Published: Nature Research 2020
• Subjects: Q Science (General); QH Natural history
• Online Access: http://eprints.um.edu.my/25251/; https://doi.org/10.1038/s41467-019-14139-5

Carbapenem-resistant Enterobacteriaceae (CRE) represent an urgent threat to human health. Here we report the application of several complementary whole-genome sequencing (WGS) technologies to characterise a hospital outbreak of blaIMP-4 carbapenemase-producing E. hormaechei. Using Illumina sequencin...