The preparation of in vivo lead x-ray fluorescence system using 99mTc

• Main Authors: Amin, Yusoff Mohd, Mahat, R.H., Loon, W.M.
• Format: Conference or Workshop Item
• Language: English
• Published: 2005
• Subjects: Q Science (General); QC Physics
• Online Access: http://eprints.um.edu.my/25043/1/ThePreparation%20of%20InVivo%20LeadX-ray%20Fluorescence%20System%20Using%2099m%20Tc.pdf; http://eprints.um.edu.my/25043/; https://www.osaka-u.ac.jp/en/international/action/network/forum

99mTc is widely used in hospital for nuc1ear medical examination such as scintigraphy of brain and thyroid. The gamma energy emitted by the 99mTc (140.50 keY) is used to produce X-ray fluorescence of the lead atoms present in bones. Being an internal source it is expected the fluorescence efficiency to increase. Using a surface barrier X-ray detection system, we have found the minimum detectable concentration (MDC), of lead in bone phantom, is 500 ppm using K-edge X-ray. The bone phantom consists of 10 ml polythene test-tube filled with saline solution and sodium (99mTc) pertechnetate of activity ranging from 7.4 III MBq. The counting time varies from 1-2 hour depending on the activity and lead concentration.