Insights into Heterologous Biosynthesis of Arteannuin B and Artemisinin in Physcomitrella patens

• Main Authors: Ikram, Nur Kusaira Khairul, Kashkooli, Arman Beyraghdar, Peramuna, Anantha, Krol, Alexander R. van der, Bouwmeester, Harro, Simonsen, Henrik Toft
• Format: Article
• Published: MDPI 2019
• Subjects: Q Science (General); QH Natural history
• Online Access: http://eprints.um.edu.my/24075/; https://doi.org/10.3390/molecules24213822

Metabolic engineering is an integrated bioengineering approach, which has made considerable progress in producing terpenoids in plants and fermentable hosts. Here, the full biosynthetic pathway of artemisinin, originating from Artemisia annua, was integrated into the moss Physcomitrella patens. Diff...