Predictive risk factors for complicated pneumonia in Malaysian children

Aim: To investigate baseline characteristics associated with complicated community-acquired pneumonia (CAPc) in Malaysian children. CAPc, such as pleural effusion and/or empyema, is on the rise, especially in Southeast Asian children, and the reasons for this are unknown. Methods: A retrospective st...

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Bibliographic Details
Main Authors: Ooi, Jian Min, Eg, Kah Peng, Chinna, Karuthan, Nathan, Anna Marie, De Bruyne, Jessie Anne, Thavagnanam, Surendran
Format: Article
Published: Wiley 2019
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Online Access:http://eprints.um.edu.my/23789/
https://doi.org/10.1111/jpc.14213
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Summary:Aim: To investigate baseline characteristics associated with complicated community-acquired pneumonia (CAPc) in Malaysian children. CAPc, such as pleural effusion and/or empyema, is on the rise, especially in Southeast Asian children, and the reasons for this are unknown. Methods: A retrospective study was conducted on all children aged 2–16 years who were admitted to the University Malaya Medical Centre with community-acquired pneumonia between 2012 and 2014. Results: In this study, of the 343 children, 58 (17%) developed CAPc. Chinese ethnicity (P < 0.001), reduced breastfeeding duration (P = 0.003), not receiving outpatient antibiotic (P < 0.001) and exposure to parental smoking (P < 0.001) were identified as risk factors for CAPc. Markedly increased respiratory rate (P = 0.021) and thrombocytosis (P < 0.001) were noted as the clinical parameters for CAPc. Conclusion: This study identifies some modifiable risk to reduce the burden of pneumonia complications. © 2018 Paediatrics and Child Health Division (The Royal Australasian College of Physicians)