Fluorometric and Docking Analysis of the Complex Formation between an Anti-Cancer Drug, Chlorambucil and Bovine Serum Albumin

• Main Authors: Saufi, Aimi Nabila Mohamad, Ridzwan, Nor Farrah Wahidah, Mohamad, Saharuddin, Tayyab, Saad, Abd Halim, Adyani Azizah
• Format: Article
• Published: Association of Pharmaceutical Teachers of India 2019
• Subjects: Q Science (General); QH Natural history; QR Microbiology
• Online Access: http://eprints.um.edu.my/23512/; https://doi.org/10.5530/ijper.53.4.131

Background: To characterize the interaction between chlorambucil (CHB) and the carrier protein, bovine serum albumin (BSA) in order to understand the transport of this drug in blood circulation. Methods: Fluorescence quenching titration method was used to examine the interaction of CHB with BSA by d...