Cell surface α2,3-linked sialic acid facilitates Zika virus internalization

• Main Authors: Tan, Chee Wah, Huan Hor, Catherine Hong, Kwek, Swee Sen, Tee, Han Kang, Sam, I-Ching, Goh, Eyleen L.K., Ooi, Eng Eong, Chan, Yoke Fun, Wang, Lin Fa
• Format: Article
• Published: Taylor & Francis Open 2019
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/23314/; https://doi.org/10.1080/22221751.2019.1590130

The emergence of neurotropic Zika virus (ZIKV) raised a public health emergency of global concern. ZIKV can cross the placental barrier and infect foetal brains, resulting in microcephaly, but the pathogenesis of ZIKV is poorly understood. With recent findings reporting AXL as a type I interferon an...