Plasmodium knowlesi exhibits distinct in vitro drug susceptibility profiles from those of Plasmodium falciparum

• Main Authors: van Schalkwyk, Donelly A., Blasco, Benjamin, Davina Nuñez, Rocio, Liew, Jonathan Wee Kent, Amir, Amirah, Lau, Yee Ling, Leroy, Didier, Moon, Robert W, Sutherland, Colin J.
• Format: Article
• Published: Elsevier 2019
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/23209/; https://doi.org/10.1016/j.ijpddr.2019.02.004

New antimalarial agents are identified and developed after extensive testing on Plasmodium falciparum parasites that can be grown in vitro. These susceptibility studies are important to inform lead optimisation and support further drug development. Until recently, little was known about the suscepti...