Gender differences in reduced substance P (SP) in children with slow-transit constipation

• Main Authors: Yik, Yee Ian, Farmer, Pamela J., King, Sebastian K., Chow, C.W., Hutson, John M., Southwell, Bridget R.
• Format: Article
• Published: Springer Verlag 2011
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/23043/; https://doi.org/10.1007/s00383-011-2852-1

Purpose: Adult slow-transit constipation (STC) occurs predominantly in females and is associated with low numbers of substance P (SP)-containing nerves in colonic circular muscle. Aim: To determine if reduced SP nerves is female predominant in paediatric STC. Methods: Children with STC were identifi...