Smart combination of β-cyclodextrin polymer-conjugated magnetic nanosorbent for potential adsorption of deoxyribonucleic acid

• Main Authors: Goh, Ying Hwa, Boon, Yih Hui, Jairaj Moses, Emmanuel, Shahriman, Mohamad Shariff, Md Yusoff, Masrudin, Yahaya, Noorfatimah, Sambasevam, Kavirajaa Pandian, Surikumaran, Hemavathy, Chandrasekaram, Kumuthini, Raoov, Muggundha
• Format: Article
• Published: Taylor & Francis 2019
• Subjects: Q Science (General); QD Chemistry
• Online Access: http://eprints.um.edu.my/22965/; https://doi.org/10.1080/01496395.2018.1524485

We reported the synthesis and characterization of Fe 3 O 4 magnetic nanoparticles modified β-cyclodextrin polymer (MNP@βCD-TDI) for the adsorption of deoxyribonucleic acid (DNA). The synthesized MNP@βCD-TDI was characterized by Fourier Transform Infra-Red spectroscopy and Vibrating Sample Magnetometer. Experiments were performed in a batch mode and parameters that affected the DNA adsorption were investigated. An evaluation of the adsorption behavior revealed that Freundlich model and pseudo-second-order fit the equilibrium data. The adsorption efficiency of DNA was found to be at 70 ± 5 % after being recycled three times. This study could be used as a general platform for future work on DNA adsorption and enrichment.