Facile Intramolecular Cyclization of N -(2-Hydroxybenzoyl)hydrazones to N ,N′ -Diacetyl Benzo-1,3,4-oxadiazepine Derivatives

• Main Authors: Chan, Pei Qie, Lee, Yean Kee, Abd Rahman, Noorsaadah
• Format: Article
• Published: Wiley-VCH Verlag 2018
• Subjects: Q Science (General); QD Chemistry
• Online Access: http://eprints.um.edu.my/22279/; https://doi.org/10.1002/ajoc.201800014

A facile synthesis of seven-membered benzo-1,3,4-oxadiazepines through one-step intramolecular cyclization of N-(2-hydroxybenzoyl)hydrazones has been established. The catalytic and substituent effects on the reactivity of this intramolecular cyclization were investigated. Through this strategy, a se...