Resveratrol analogue, (E)-N-(2-(4-methoxystyryl) phenyl) furan-2-carboxamide induces G2/M cell cycle arrest through the activation of p53–p21CIP1/WAF1 in human colorectal HCT116 cells

• Main Authors: Cheah, Foo Kit, Leong, Kok Hoong, Thomas, Noel Francis, Chin, Hui Kee, Ariffin, Azhar, Awang, Khalijah
• Format: Article
• Published: Springer 2018
• Subjects: Q Science (General); QD Chemistry; R Medicine
• Online Access: http://eprints.um.edu.my/22262/; https://doi.org/10.1007/s10495-018-1457-8

Resveratrol, a naturally occurring polyphenolic antioxidant, is a potential chemoprophylactic agent for various cancers, including colorectal cancer. Although emerging evidence continually suggests that a number of resveratrol derivatives may be better cancer chemopreventive candidates than resverat...