Activation of autophagy by stress-activated signals as a cellular self-defense mechanism against the cytotoxic effects of MBIC in human breast cancer cells in vitro

We recently reported that methyl 2-(-5-fluoro-2-hydroxyphenyl)-1H-benzo[d]imidazole-5-carboxylate (MBIC) is a microtubule targeting agent (MTA) with multiple mechanisms of action including apoptosis in two human breast cancer cell-lines MCF-7 and MDA-MB-231. In the present study, investigation of ea...

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Bibliographic Details
Main Authors: Hasanpourghadi, Mohadeseh, Majid, Nazia Abdul, Mustafa, Mohd Rais
Format: Article
Published: Elsevier 2018
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Online Access:http://eprints.um.edu.my/21929/
https://doi.org/10.1016/j.bcp.2018.03.030
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