Comparative genomic analysis of ten clinical Streptococcus pneumoniae collected from a Malaysian hospital reveal 31 new unique drug-resistant SNPs using whole genome sequencing

• Main Authors: Jindal, Hassan Mahmood, Ramanathan, Babu, Le, Cheng Foh, Gudimella, Ranganath, Razali, Rozaimi, Manikam, Rishya, Sekaran, Shamala Devi
• Format: Article
• Published: BMC 2018
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/21736/; https://doi.org/10.1186/s12929-018-0414-8

Background: Streptococcus pneumoniae or pneumococcus is a leading cause of morbidity and mortality worldwide, specifically in relation to community-acquired pneumonia. Due to the overuse of antibiotics, S. pneumoniae has developed a high degree of resistance to a wide range of antibacterial drugs. M...