Determinants of quality of life and psychological status in adults with psoriasis
We investigated whether disease severity and clinical manifestations were associated with depression, anxiety, stress and quality of life in adults with psoriasis. Participants were recruited from a dermatology outpatient clinic at a teaching hospital. Information on sociodemographic characteristics...
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my.um.eprints.215682019-06-27T08:17:06Z http://eprints.um.edu.my/21568/ Determinants of quality of life and psychological status in adults with psoriasis Kwan, Zhenli Bong, Yii Bonn Tan, Leng Leng Lim, Shu Xian Yong, Adrian Sze Wai Ch'ng, Chin Chwen Tan, Maw Pin Ismail, Rokiah R Medicine We investigated whether disease severity and clinical manifestations were associated with depression, anxiety, stress and quality of life in adults with psoriasis. Participants were recruited from a dermatology outpatient clinic at a teaching hospital. Information on sociodemographic characteristics, disease severity, presence of arthropathy and head involvement was specifically recorded. Disease severity was assessed using the Psoriasis Area and Severity Index (PASI). Quality of life and psychological symptoms were measured using the Dermatology Life Quality Index (DLQI) and the Depression Anxiety Stress Scale (DASS), respectively. One hundred individuals were recruited. Unadjusted analysis revealed that head involvement was associated with depression [odds ratio (OR) 8.509; 95% confidence interval (CI) 1.077–67.231] and anxiety (OR 6.46; 95% CI 1.401–29.858). Severe disease was associated with a poorer quality of life compared to mild disease (OR 3.750; 95% CI 1.330–10.577). Younger age was associated with an increased risk of depression [mean difference (MD) − 8.640; 95% CI − 16.390 to − 0.890], anxiety (MD − 11.553; 95% CI − 18.478 to− 4.628), stress (MD − 11.440; 95% CI − 19.252 to − 3.628) and severely impaired quality of life (MD − 12.338; 95% CI − 19.548 to − 5.127). Following adjustments for age and disease severity, anxiety, stress and depression remained associated with severely impaired quality of life. Springer 2018 Article PeerReviewed Kwan, Zhenli and Bong, Yii Bonn and Tan, Leng Leng and Lim, Shu Xian and Yong, Adrian Sze Wai and Ch'ng, Chin Chwen and Tan, Maw Pin and Ismail, Rokiah (2018) Determinants of quality of life and psychological status in adults with psoriasis. Archives of Dermatological Research, 310 (5). pp. 443-451. ISSN 0340-3696 https://doi.org/10.1007/s00403-018-1832-x doi:10.1007/s00403-018-1832-x |
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R Medicine Kwan, Zhenli Bong, Yii Bonn Tan, Leng Leng Lim, Shu Xian Yong, Adrian Sze Wai Ch'ng, Chin Chwen Tan, Maw Pin Ismail, Rokiah Determinants of quality of life and psychological status in adults with psoriasis |
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We investigated whether disease severity and clinical manifestations were associated with depression, anxiety, stress and quality of life in adults with psoriasis. Participants were recruited from a dermatology outpatient clinic at a teaching hospital. Information on sociodemographic characteristics, disease severity, presence of arthropathy and head involvement was specifically recorded. Disease severity was assessed using the Psoriasis Area and Severity Index (PASI). Quality of life and psychological symptoms were measured using the Dermatology Life Quality Index (DLQI) and the Depression Anxiety Stress Scale (DASS), respectively. One hundred individuals were recruited. Unadjusted analysis revealed that head involvement was associated with depression [odds ratio (OR) 8.509; 95% confidence interval (CI) 1.077–67.231] and anxiety (OR 6.46; 95% CI 1.401–29.858). Severe disease was associated with a poorer quality of life compared to mild disease (OR 3.750; 95% CI 1.330–10.577). Younger age was associated with an increased risk of depression [mean difference (MD) − 8.640; 95% CI − 16.390 to − 0.890], anxiety (MD − 11.553; 95% CI − 18.478 to− 4.628), stress (MD − 11.440; 95% CI − 19.252 to − 3.628) and severely impaired quality of life (MD − 12.338; 95% CI − 19.548 to − 5.127). Following adjustments for age and disease severity, anxiety, stress and depression remained associated with severely impaired quality of life. |
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Article |
author |
Kwan, Zhenli Bong, Yii Bonn Tan, Leng Leng Lim, Shu Xian Yong, Adrian Sze Wai Ch'ng, Chin Chwen Tan, Maw Pin Ismail, Rokiah |
author_facet |
Kwan, Zhenli Bong, Yii Bonn Tan, Leng Leng Lim, Shu Xian Yong, Adrian Sze Wai Ch'ng, Chin Chwen Tan, Maw Pin Ismail, Rokiah |
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Kwan, Zhenli |
title |
Determinants of quality of life and psychological status in adults with psoriasis |
title_short |
Determinants of quality of life and psychological status in adults with psoriasis |
title_full |
Determinants of quality of life and psychological status in adults with psoriasis |
title_fullStr |
Determinants of quality of life and psychological status in adults with psoriasis |
title_full_unstemmed |
Determinants of quality of life and psychological status in adults with psoriasis |
title_sort |
determinants of quality of life and psychological status in adults with psoriasis |
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Springer |
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2018 |
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http://eprints.um.edu.my/21568/ https://doi.org/10.1007/s00403-018-1832-x |
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1643691596817891328 |
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13.18916 |