Regulation of Apoptotic Effects by Erythrocarpine E, a Cytotoxic Limonoid from Chisocheton erythrocarpus in HSC-4 Human Oral Cancer Cells

• Main Authors: Nagoor, N.H., Shah, J.M.N., Soon, L.C., In, L.L., Mohammad, K., Awang, K.
• Format: Article
• Language: English
• Published: 2011
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/2156/1/1.pdf; http://eprints.um.edu.my/2156/; http://www.ncbi.nlm.nih.gov/pubmed/21858194

The aim of this study was to determine the cytotoxic and apoptotic effects of erythrocarpine E (CEB4), a limonoid extracted from Chisocheton erythrocarpus on human oral squamous cell carcinoma. Based on preliminary dimethyl-2-thiazolyl-2,5-diphenyl-2H-tetrazolium bromide (MTT) assays, CEB4 treated H...