Gly-Val-Arg, an angiotensin-I-converting enzyme inhibitory tripeptide ameliorates hypertension on spontaneously hypertensive rats

• Main Authors: Manoharan, Sivananthan, Shuib, Adawiyah Suriza, Abdullah, Noorlidah, Ashrafzadeh, Ali, Kabir, Nurul
• Format: Article
• Published: Elsevier 2018
• Subjects: Q Science (General); QH Natural history; R Medicine
• Online Access: http://eprints.um.edu.my/21344/; https://doi.org/10.1016/j.procbio.2018.03.014

The tripeptide GVR was previously shown to inhibit ACE and was able to reduce systolic blood pressure in SHRs within 6 h after administration. To further analyse the potential of tripeptide GVR in lowering blood pressure, a long term study was carried out where the tripeptide was orally administered...