Leptin and its receptor: can they help to differentiate chromophobe renal cell carcinoma from renal oncocytoma?

• Main Authors: Ng, Keng Lim, Del Vecchio, Sharon Juliet, Samaratunga, Hemamali, Morais, Christudas, Rajandram, Retnagowri, Vesey, David A., Wood, Simon Thomas, Gobe, Glenda Carolyn
• Format: Article
• Published: Lippincott Williams & Wilkins 2018
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/21143/; https://doi.org/10.1016/j.pathol.2018.01.007

One of the challenges in differentiating chromophobe renal cell carcinoma (chRCC) from benign renal oncocytoma (RO) is overlapping morphology between the two subtypes. The aim of this study was to investigate the usefulness of expression of leptin (Ob) and its receptor (ObR) in discriminating chRCC...