Discovery of New Genes Involved in Curli Production by a Uropathogenic Escherichia coli Strain from the Highly Virulent O45:K1:H7 Lineage

• Main Authors: Nhu, Nguyen Thi Khanh, Phan, Minh-Duy, Peters, Kate M., Lo, Alvin W., Forde, Brian M., Chong, Teik Min, Yin, Wai Fong, Chan, Kok Gan, Chromek, Milan, Brauner, Annelie, Chapman, Matthew R., Beatson, Scott A., Schembri, Mark A., Justice, Sheryl
• Format: Article
• Published: American Society for Microbiology 2018
• Subjects: Q Science (General); QH Natural history
• Online Access: http://eprints.um.edu.my/21130/; https://doi.org/10.1128/mBio.01462-18

Curli are bacterial surface-associated amyloid fibers that bind to the dye Congo red (CR) and facilitate uropathogenic Escherichia coli (UPEC) biofilm formation and protection against host innate defenses. Here we sequenced the genome of the curli-producing UPEC pyelonephritis strain MS7163 and show...