Ceramicines M–P from Chisocheton ceramicus: isolation and structure–activity relationship study

• Main Authors: Nugroho, Alfarius Eko, Hashimoto, Akiyo, Wong, Chin-Piow, Yokoe, Hiromasa, Tsubuki, Masayoshi, Kaneda, Toshio, A. Hadi, A. Hamid, Morita, Hiroshi
• Format: Article
• Published: Springer Verlag (Germany) 2018
• Subjects: Q Science (General); QD Chemistry
• Online Access: http://eprints.um.edu.my/21098/; https://doi.org/10.1007/s11418-017-1109-2

Ceramicines are a series of limonoids which were isolated from the bark of Malaysian Chisocheton ceramicus (Meliaceae) and show various biological activities. Ceramicine B, in particular, has been reported to show a strong lipid droplet accumulation (LDA) inhibitory activity on a mouse pre-adipocyte...