T-Cell Exhaustion in Chronic Infections: Reversing the State of Exhaustion and Reinvigorating Optimal Protective Immune Responses
T-cell exhaustion is a phenomenon of dysfunction or physical elimination of antigen-specific T cells reported in human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) infections as well as cancer. Exhaustion appears to be often restricted to CD8+ T cells responses...
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Main Authors: | Saeidi, Alireza, Zandi, Keivan, Cheok, Yi Ying, Saeidi, Hamidreza, Wong, Won Fen, Lee, Chalystha Yie Qin, Cheong, Heng Choon, Yong, Yean Kong, Larsson, Marie, Shankar, Esaki Muthu |
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Format: | Article |
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Frontiers Media
2018
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Online Access: | http://eprints.um.edu.my/20831/ https://doi.org/10.3389/fimmu.2018.02569 |
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