LMTK3 confers chemo-resistance in breast cancer

• Main Authors: Stebbing, Justin, Shah, Kalpit, Lit, Lei Cheng, Gagliano, Teresa, Ditsiou, Angeliki, Wang, Tingting, Wendler, Franz, Simon, Thomas, Szabó, Krisztina Sára, O’Hanlon, Timothy, Dean, Michael, Roslani, April Camilla, Cheah, Swee Hung, Lee, Soo Chin, Giamas, Georgios
• Format: Article
• Published: Springer Nature 2018
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/20613/; https://doi.org/10.1038/s41388-018-0197-0

Lemur tyrosine kinase 3 (LMTK3) is an oncogenic kinase that is involved in different types of cancer (breast, lung, gastric, colorectal) and biological processes including proliferation, invasion, migration, chromatin remodeling as well as innate and acquired endocrine resistance. However, the role...