Pahangine A and B, two new oxetane containing neolignans from the barks of Beilschmiedia glabra Kosterm (Lauraceae)

Phytochemical investigation on the barks of Beilschmiedia glabra Kosterm led to the isolation of two new oxetane containing neolignans, Pahangine A (1) and Pahangine B (2) together with eight known compounds. The structures of isolated compounds were elucidated by extensive spectroscopic analysis in...

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Bibliographic Details
Main Authors: Sulaiman, Syazreen Nadia, Zahari, Azeana, Liew, Sook Yee, Litaudon, Marc, Issam, A.M., Wahab, Habibah A., Awang, Khalijah
Format: Article
Published: Elsevier 2018
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Online Access:http://eprints.um.edu.my/20598/
https://doi.org/10.1016/j.phytol.2018.03.008
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Summary:Phytochemical investigation on the barks of Beilschmiedia glabra Kosterm led to the isolation of two new oxetane containing neolignans, Pahangine A (1) and Pahangine B (2) together with eight known compounds. The structures of isolated compounds were elucidated by extensive spectroscopic analysis including 1D and 2D NMR (1H–1H COSY, HSQC, and HMBC), DEPT-Q NMR, and by comparing with the published data. A possible biosynthetic pathway for the formation of 1 and 2 was proposed.