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Renewable resources-based approach to biantennary glycolipids

A new synthesis approach towards biantennary lipids of Guerbet glycoside type was developed based on oleic acid as sustainable resource. Functionalization of the double bond provided access to primary alcohols with α-branched C19-skeleton. Formulation studies with corresponding lactosides indicated...

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Main Authors: Tabandeh, Mojtaba, Salman, Abbas Abdulameer, Goh, Ean Wai, Heidelberg, Thorsten, Hussen, Rusnah Syahila Duali
Format: Article
Published: Elsevier 2018
Subjects:
Q Science (General)
QD Chemistry
Online Access:http://eprints.um.edu.my/20584/
https://doi.org/10.1016/j.chemphyslip.2018.01.011
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spelling my.um.eprints.205842019-03-04T07:44:36Z http://eprints.um.edu.my/20584/ Renewable resources-based approach to biantennary glycolipids Tabandeh, Mojtaba Salman, Abbas Abdulameer Goh, Ean Wai Heidelberg, Thorsten Hussen, Rusnah Syahila Duali Q Science (General) QD Chemistry A new synthesis approach towards biantennary lipids of Guerbet glycoside type was developed based on oleic acid as sustainable resource. Functionalization of the double bond provided access to primary alcohols with α-branched C19-skeleton. Formulation studies with corresponding lactosides indicated formation of vesicles with high assembly stability. A relatively narrow bimodal size distribution of the latter, which turns into a narrow unimodal distribution of small vesicles upon addition of an ionic cosurfactant, suggests potential for a vesicular drug delivery system. Elsevier 2018 Article PeerReviewed Tabandeh, Mojtaba and Salman, Abbas Abdulameer and Goh, Ean Wai and Heidelberg, Thorsten and Hussen, Rusnah Syahila Duali (2018) Renewable resources-based approach to biantennary glycolipids. Chemistry and Physics of Lipids, 212. pp. 111-119. ISSN 0009-3084 https://doi.org/10.1016/j.chemphyslip.2018.01.011 doi:10.1016/j.chemphyslip.2018.01.011
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic Q Science (General)
QD Chemistry
spellingShingle Q Science (General)
QD Chemistry
Tabandeh, Mojtaba
Salman, Abbas Abdulameer
Goh, Ean Wai
Heidelberg, Thorsten
Hussen, Rusnah Syahila Duali
Renewable resources-based approach to biantennary glycolipids
description A new synthesis approach towards biantennary lipids of Guerbet glycoside type was developed based on oleic acid as sustainable resource. Functionalization of the double bond provided access to primary alcohols with α-branched C19-skeleton. Formulation studies with corresponding lactosides indicated formation of vesicles with high assembly stability. A relatively narrow bimodal size distribution of the latter, which turns into a narrow unimodal distribution of small vesicles upon addition of an ionic cosurfactant, suggests potential for a vesicular drug delivery system.
format Article
author Tabandeh, Mojtaba
Salman, Abbas Abdulameer
Goh, Ean Wai
Heidelberg, Thorsten
Hussen, Rusnah Syahila Duali
author_facet Tabandeh, Mojtaba
Salman, Abbas Abdulameer
Goh, Ean Wai
Heidelberg, Thorsten
Hussen, Rusnah Syahila Duali
author_sort Tabandeh, Mojtaba
title Renewable resources-based approach to biantennary glycolipids
title_short Renewable resources-based approach to biantennary glycolipids
title_full Renewable resources-based approach to biantennary glycolipids
title_fullStr Renewable resources-based approach to biantennary glycolipids
title_full_unstemmed Renewable resources-based approach to biantennary glycolipids
title_sort renewable resources-based approach to biantennary glycolipids
publisher Elsevier
publishDate 2018
url http://eprints.um.edu.my/20584/
https://doi.org/10.1016/j.chemphyslip.2018.01.011
_version_ 1643691322193739776
score 13.18916

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