Molecular Genetic Characterization of Patients With Focal Epilepsy Using a Customized Targeted Resequencing Gene Panel

• Main Authors: Tsai, Meng Han, Chan, Chung Kin, Chang, Ying Chao, Lin, Chih Hsiang, Liou, Chia Wei, Chang, Wen Neng, Ng, Ching Ching, Lim, Kheng Seang, Hwang, Daw Yang
• Format: Article
• Published: Frontiers Media 2018
• Subjects: Q Science (General); QH Natural history; R Medicine
• Online Access: http://eprints.um.edu.my/20454/; https://doi.org/10.3389/fneur.2018.00515

Objective: Focal epilepsy is the most common subtype of epilepsies in which the influence of underlying genetic factors is emerging but remains largely uncharacterized. The purpose of this study is to determine the contribution of currently known disease-causing genes in a large cohort (n = 593) of...