Stepwise evolution of pandrug-resistance in Klebsiella pneumoniae

• Main Authors: Zowawi, H.M., Forde, B.M., Alfaresi, M., Alzarouni, A., Farahat, Y., Chong, T.M., Yin, Wai Fong, Chan, Kok Gan, Li, J., Schembri, M.A., Beatson, S.A., Paterson, D.L.
• Format: Article
• Published: Nature Publishing Group 2015
• Subjects: Q Science (General); QH Natural history
• Online Access: http://eprints.um.edu.my/19265/; http://dx.doi.org/10.1038/srep15082

Carbapenem resistant Enterobacteriaceae (CRE) pose an urgent risk to global human health. CRE that are non-susceptible to all commercially available antibiotics threaten to return us to the pre-antibiotic era. Using Single Molecule Real Time (SMRT) sequencing we determined the complete genome of a p...