Association of copy number variations in complement factor H-Related genes among age-related macular degenerative subjects

• Main Authors: Bakri, N.M., Ramachandran, V., Kee, H.F., Subrayan, V., Isa, H., Ngah, N.F., Mohamad, N.A., Mooi, C.S., Mun, C.Y., Ismail, P., Ismail, F., Sukiman, E.S., Wan Sulaiman, W.A.
• Format: Article
• Published: Elsevier 2017
• Subjects: R Medicine; RE Ophthalmology
• Online Access: http://eprints.um.edu.my/19231/; http://dx.doi.org/10.1016/j.kjms.2017.08.003

Age-related macular degeneration (AMD) is the most widely recognised cause of irreversible vision loss and previous studies have suggested that the advancement of wet AMD is influenced by both modifiable and non-modifiable elements. Single nucleotide polymorphism (SNPs) and copy number of variations...