Phenotypic and microRNA transcriptomic profiling of the MDA-MB-231 spheroid-enriched CSCs with comparison of MCF-7 microRNA profiling dataset

• Main Authors: Boo, L., Ho, W.Y., Ali, N.M., Yeap, S.K., Ky, H., Chan, Kok Gan, Yin, W.F., Satharasinghe, D.A., Liew, W.C., Tan, S.W., Cheong, S.K., Ong, H.K.A.
• Format: Article
• Published: PeerJ 2017
• Subjects: Q Science (General); QH Natural history
• Online Access: http://eprints.um.edu.my/19221/; http://dx.doi.org/10.7717/peerj.3551

Breast cancer spheroids have been widely used as in vitro models of cancer stem cells (CSCs), yet little is known about their phenotypic characteristics and microRNAs (miRNAs) expression profiles. The objectives of this research were to evaluate the phenotypic characteristics of MDA-MB-231 spheroid-...