Synthesis and gastroprotective activities of some zinc (II) complexes derived from (E)-2-(1-(2-(piperazin-1-yl)ethylimino)ethyl)phenol and (E)-4-(1-(2-(piperazin-1-yl)ethylimino)ethyl)benzene-1,3-diol Schiff bases against aspirin induced ulceration

• Main Authors: Salga, M.S., Ali, Hapipah Mohd, Abdulla, Mahmood Ameen, Abdelwahab, S.I., ElhassanTaha, M.M., Yagoub, U.
• Format: Article
• Published: Elsevier 2017
• Subjects: QD Chemistry; R Medicine
• Online Access: http://eprints.um.edu.my/19036/; http://dx.doi.org/10.1016/j.arabjc.2013.05.028

This study describes the protective effects of piperazine derived compounds against aspirin induced gastric injuries and evaluated the role of nitric oxide, inflammatory cytokines and serum level of aspartate aminotransaminases (AST), alanine aminotransaminases (ALT), high density lipoprotein (HDL)...