Decrease of CD69 levels on TCR Vα7.2+CD4+ innate-like lymphocytes is associated with impaired cytotoxic functions in chronic hepatitis B virus-infected patients

• Main Authors: Yong, Y.K., Tan, H.Y., Saeidi, A., Mohamed, R., Atiya, N., Ansari, A.W., Rajarajeswaran, J., Vadivelu, J., Velu, V., Larsson, M., Shankar, E.M.
• Format: Article
• Published: SAGE Publications (UK and US) 2017
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/18898/; http://dx.doi.org/10.1177/1753425917714854

Hepatitis B virus (HBV) infection is a major cause of chronic liver disease that may progress to liver cirrhosis and hepatocellular carcinoma. Host immune responses represent the key determinants of HBV clearance or persistence. Here, we investigated the role of the early activation marker, CD69 and...