Immunity in young adult survivors of childhood leukemia is similar to the elderly rather than age-matched controls: Role of cytomegalovirus

• Main Authors: Azanan, M.S., Abdullah, N.K., Chua, L.L., Lum, S.H., Abdul Ghafar, S.S., Kamarulzaman, A., Kamaruzzaman, S., Lewin, S.R., Woo, Y.L., Ariffin, H., Rajasuriar, R.
• Format: Article
• Published: John Wiley & Sons 2016
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/18401/; https://doi.org/10.1002/eji.201646356

Many treatment complications that occur late in childhood cancer survivors resemble age-related comorbidities observed in the elderly. An immune phenotype characterized by increased immune activation, systemic inflammation, and accumulation of late-differentiated memory CD57+CD28− T cells has been a...