Synthesis and biological evaluation of indole core-based derivatives with potent antibacterial activity against resistant bacterial pathogens

• Main Authors: Hong, W., Li, J., Chang, Z., Tan, X., Yang, H., Ouyang, Y., Yang, Y., Kaur, S., Paterson, I.C., Ngeow, Y.F., Wang, H.
• Format: Article
• Language: English
• Published: Nature Publishing Group 2017
• Subjects: RK Dentistry
• Online Access: http://eprints.um.edu.my/17797/1/Synthesis_and_biological.pdf; http://eprints.um.edu.my/17797/; http://www.nature.com/ja/journal/v70/n7/full/ja201755a.html

The emergence of drug resistance in bacterial pathogens is a growing clinical problem that poses difficult challenges in patient management. To exacerbate this problem, there is currently a serious lack of antibacterial agents that are designed to target extremely drug-resistant bacterial strains. H...