Anticancer activity of a monobenzyltin complex C1 against MDA-MB-231 cells through induction of Apoptosis and inhibition of breast cancer stem cells

• Main Authors: Fani, S., Kamalidehghan, B., Lo, Kong Mun, Nigjeh, S.E., Keong, Y.S., Dehghan, F., Soori, R., Abdulla, Mahmood Ameen, Chow, K.M., Ali, Hapipah Mohd, Hajiaghaalipour, F., Rouhollahi, E., Hashim, N.M.
• Format: Article
• Language: English
• Published: Nature Publishing Group 2016
• Subjects: Q Science (General); R Medicine
• Online Access: http://eprints.um.edu.my/17694/1/Fani%2C_S._%282016%29.pdf; http://eprints.um.edu.my/17694/; http://dx.doi.org/10.1038/srep38992

In the present study, we examined the cytotoxic effects of Schiff base complex, [N-(3,5-dichloro-2-oxidobenzylidene)-4-chlorobenzyhydrazidato](o-methylbenzyl)aquatin(IV) chloride, and C1 on MDA-MB-231 cells and derived breast cancer stem cells from MDA-MB-231 cells. The acute toxicity experiment wit...