Endoscopic Submucosal Dissection Outcomes for Gastroesophageal Tumors in Low Volume Units: A Multicenter Survey

Background and Aims. Endoscopic submucosal dissection (ESD) outcomes have traditionally been reported from high volume centers in East Asia. Data from low volume centers in other parts of Asia remain sparse. Methods. A retrospective survey with a structured questionnaire of 5 tertiary centers in 3 c...

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Main Authors: Najib Azmi, A., Khor, C.J.L., Ho, K.Y., Pittayanon, R., Rerknimitr, R., Ratanachu-ek, T., Koay, D.S.C., Koh, J.C., Ho, S.H., Goh, K.L., Mahadeva, S.
Format: Article
Language:English
Published: Hindawi Publishing Corporation 2016
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Online Access:http://eprints.um.edu.my/17519/1/AzmiAN_%282016%29.pdf
http://eprints.um.edu.my/17519/
http://dx.doi.org/10.1155/2016/5670564
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spelling my.um.eprints.175192017-07-17T03:42:23Z http://eprints.um.edu.my/17519/ Endoscopic Submucosal Dissection Outcomes for Gastroesophageal Tumors in Low Volume Units: A Multicenter Survey Najib Azmi, A. Khor, C.J.L. Ho, K.Y. Pittayanon, R. Rerknimitr, R. Ratanachu-ek, T. Koay, D.S.C. Koh, J.C. Ho, S.H. Goh, K.L. Mahadeva, S. R Medicine Background and Aims. Endoscopic submucosal dissection (ESD) outcomes have traditionally been reported from high volume centers in East Asia. Data from low volume centers in other parts of Asia remain sparse. Methods. A retrospective survey with a structured questionnaire of 5 tertiary centers in 3 countries in South East Asia was conducted. Details of training and clinical outcomes of ESD cases, with follow-up data from these centers, were analyzed. Results. Seven endoscopists from the 5 centers performed a total of 35 cases of ESD in the upper gastrointestinal tract (UGIT) over a 6-year duration. Details of the lesions excised were as follows: median size was 20 mm, morphologically 20 (68.6%) were flat/depressed and 6 (17.1%) were submucosal, and histologically 27 (77.1%) were neoplastic. The median duration of ESD procedures was 105 minutes, with an en-bloc resection rate of 91.4%. There was 1 (2.9%) case of delayed bleeding, but no perforation nor mortality in any of the cases. The recurrence rate after ESD was 5.7%. A prolonged ESD duration was influenced by a larger size of lesion (25 mm, ) but not by factors related to the training experience of endoscopists. Conclusions. ESD in the UGIT is feasible and safe in low volume centers in Asia. Hindawi Publishing Corporation 2016 Article PeerReviewed application/pdf en http://eprints.um.edu.my/17519/1/AzmiAN_%282016%29.pdf Najib Azmi, A. and Khor, C.J.L. and Ho, K.Y. and Pittayanon, R. and Rerknimitr, R. and Ratanachu-ek, T. and Koay, D.S.C. and Koh, J.C. and Ho, S.H. and Goh, K.L. and Mahadeva, S. (2016) Endoscopic Submucosal Dissection Outcomes for Gastroesophageal Tumors in Low Volume Units: A Multicenter Survey. Diagnostic and Therapeutic Endoscopy, 2016. pp. 1-7. ISSN 1070-3608 http://dx.doi.org/10.1155/2016/5670564 doi:10.1155/2016/5670564
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
language English
topic R Medicine
spellingShingle R Medicine
Najib Azmi, A.
Khor, C.J.L.
Ho, K.Y.
Pittayanon, R.
Rerknimitr, R.
Ratanachu-ek, T.
Koay, D.S.C.
Koh, J.C.
Ho, S.H.
Goh, K.L.
Mahadeva, S.
Endoscopic Submucosal Dissection Outcomes for Gastroesophageal Tumors in Low Volume Units: A Multicenter Survey
description Background and Aims. Endoscopic submucosal dissection (ESD) outcomes have traditionally been reported from high volume centers in East Asia. Data from low volume centers in other parts of Asia remain sparse. Methods. A retrospective survey with a structured questionnaire of 5 tertiary centers in 3 countries in South East Asia was conducted. Details of training and clinical outcomes of ESD cases, with follow-up data from these centers, were analyzed. Results. Seven endoscopists from the 5 centers performed a total of 35 cases of ESD in the upper gastrointestinal tract (UGIT) over a 6-year duration. Details of the lesions excised were as follows: median size was 20 mm, morphologically 20 (68.6%) were flat/depressed and 6 (17.1%) were submucosal, and histologically 27 (77.1%) were neoplastic. The median duration of ESD procedures was 105 minutes, with an en-bloc resection rate of 91.4%. There was 1 (2.9%) case of delayed bleeding, but no perforation nor mortality in any of the cases. The recurrence rate after ESD was 5.7%. A prolonged ESD duration was influenced by a larger size of lesion (25 mm, ) but not by factors related to the training experience of endoscopists. Conclusions. ESD in the UGIT is feasible and safe in low volume centers in Asia.
format Article
author Najib Azmi, A.
Khor, C.J.L.
Ho, K.Y.
Pittayanon, R.
Rerknimitr, R.
Ratanachu-ek, T.
Koay, D.S.C.
Koh, J.C.
Ho, S.H.
Goh, K.L.
Mahadeva, S.
author_facet Najib Azmi, A.
Khor, C.J.L.
Ho, K.Y.
Pittayanon, R.
Rerknimitr, R.
Ratanachu-ek, T.
Koay, D.S.C.
Koh, J.C.
Ho, S.H.
Goh, K.L.
Mahadeva, S.
author_sort Najib Azmi, A.
title Endoscopic Submucosal Dissection Outcomes for Gastroesophageal Tumors in Low Volume Units: A Multicenter Survey
title_short Endoscopic Submucosal Dissection Outcomes for Gastroesophageal Tumors in Low Volume Units: A Multicenter Survey
title_full Endoscopic Submucosal Dissection Outcomes for Gastroesophageal Tumors in Low Volume Units: A Multicenter Survey
title_fullStr Endoscopic Submucosal Dissection Outcomes for Gastroesophageal Tumors in Low Volume Units: A Multicenter Survey
title_full_unstemmed Endoscopic Submucosal Dissection Outcomes for Gastroesophageal Tumors in Low Volume Units: A Multicenter Survey
title_sort endoscopic submucosal dissection outcomes for gastroesophageal tumors in low volume units: a multicenter survey
publisher Hindawi Publishing Corporation
publishDate 2016
url http://eprints.um.edu.my/17519/1/AzmiAN_%282016%29.pdf
http://eprints.um.edu.my/17519/
http://dx.doi.org/10.1155/2016/5670564
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