Dietary cocoa inhibits colitis associated cancer: a crucial involvement of the IL-6/STAT3 pathway

• Main Authors: Saadatdoust, Z., Pandurangan, A.K., Sadagopan, S.K.A., Esa, N.M., Ismail, A., Mustafa, Mohd Rais
• Format: Article
• Published: 2015
• Subjects: Q Science (General); QD Chemistry
• Online Access: http://eprints.um.edu.my/16451/; https://doi.org/10.1016/j.jnutbio.2015.07.024

Patients with inflammatory bowel disease (IBD) are at increased risk for developing ulcerative colitis-associated colorectal cancer (CRC). The interleukin-6 (IL-6)/signal transducer and activator of transcription (STAT)-3 signaling regulates survival and proliferation of intestinal epithelial cells...