Forkhead Box Transcription Factor (FOXO3a) mediates the cytotoxic effect of vernodalin in vitro and inhibits the breast tumor growth in vivo

Background: Natural compounds have been demonstrated to lower breast cancer risk and sensitize tumor cells to anticancer therapies. Recently, we demonstrated that vernodalin (the active constituent of the medicinal herb Centratherum anthelminticum seeds) induces apoptosis in breast cancer cell-lines...

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Bibliographic Details
Main Authors: Sadagopan, S.K.A., Mohebali, N., Looi, C.Y., Hasanpourghadi, M., Pandurangan, A.K., Arya, A., Karimian, H., Mustafa, Mohd Rais
Format: Article
Published: BioMed Central 2015
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Online Access:http://eprints.um.edu.my/16226/
https://doi.org/10.1186/s13046-015-0266-y
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