The impact of antibody/epitope affinity strength on the sensitivity of electrochemical immunosensors for detecting small molecules

A displacement immunoassay involves having a labelled analogue of the analyte (the epitope) already bound to the antibody. The presence of the analyte causes a competition for antibodies, and some of the antibodies dissociates from the epitope so that it can bind with the analyte. Herein, the i...

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Bibliographic Details
Main Authors: Khor, S.M., Thordarson, P., Gooding, J.J.
Format: Article
Language:English
Published: Springer Verlag (Germany) 2013
Subjects:
Online Access:http://eprints.um.edu.my/15519/1/Analytical_and_Bioanalytical_Chemistry_405%282013%293889-3898_%28post-print_version%29.pdf
http://eprints.um.edu.my/15519/
http://dx.doi.org/10.1007/s00216-013-6782-8 http://download.springer.com/static/pdf/674/art253A10.1007252Fs00216-013-6782-8.pdf?originUrl=http3A2F2Flink.springer.com2Farticle2F10.10072Fs00216-013-6782-8&token2=exp=1450677127~acl=2Fstatic2Fpdf2F6742Fart252
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