A colloidal gold-based lateral flow immunoassay for direct determination of haemoglobin A1c in whole blood

• Main Authors: Ang, S.H., Yu, C.Y., Ang, G.Y., Chan, Y.Y., Alias, Y., Khor, S.M.
• Format: Article
• Language: English
• Published: 2015
• Subjects: QD Chemistry
• Online Access: http://eprints.um.edu.my/15513/1/Analytical_Methods_7_%282015%29_3972-3980_%28post-print_version%29.pdf; http://eprints.um.edu.my/15513/; http://dx.doi.org/10.1039/C5AY00518C http://pubs.rsc.org/en/content/articlepdf/2015/ay/c5ay00518c

We developed an immunosensor that operates based on the lateral flow principle designed to detect haemoglobin A1c (HbA1c), a biomarker for type 2 diabetes mellitus in human blood samples. Two different clones of antibodies were used to form a "sandwich" when HbA1c was present. Functionaliz...