Topical piperacillin/tazobactam for recalcitrant pseudomonas aeruginosa keratitiS

Purpose: To report the treatment of therapy-resistant Pseudomonas aeruginosa keratitis with topical piperacillin/tazobactam. Methods: Retrospective report of 3 cases. Results: Three patients with P. aeruginosa keratitis were unresponsive to various antimicrobials. Resolution of all 3 cases of kerati...

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Main Authors: Chew, F.L.M., Soong, T.K., Shin, H.C., Samsudin, A., Visvaraja, S.
Format: Article
Published: Mary Ann Liebert Inc 2010
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Online Access:http://eprints.um.edu.my/14919/
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Summary:Purpose: To report the treatment of therapy-resistant Pseudomonas aeruginosa keratitis with topical piperacillin/tazobactam. Methods: Retrospective report of 3 cases. Results: Three patients with P. aeruginosa keratitis were unresponsive to various antimicrobials. Resolution of all 3 cases of keratitis occurred upon commencement of topical piperacillin/tazobactam. Conclusion: Therapy-resistant P. aeruginosa keratitis acquired from the community is becoming an increasing problem. Topical piperacillin/tazobactam is an option for the treatment of therapy-resistant P. aeruginosa keratitis.